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Symbol
Name
ID
Trp53
transformation related protein 53
MGI:98834
Phenotype annotations related to respiratory system
Darker colors indicate more annotations
Human Phenotypes
Neoplasia of the nasopharynx
Pleural effusion
Neoplasm of the lung
Lung adenocarcinoma
Neoplasm of the larynx
Disease(s) Associated with TP53
Li-Fraumeni syndrome
Li-Fraumeni syndrome 1
multiple myeloma
nasopharynx carcinoma

Mouse Phenotypes
lung inflammation
increased lung adenoma incidence
increased lung adenocarcinoma incidence
increased lung tumor incidence
pulmonary fibrosis
Availability Mouse Genotype
Trp53tm1.1Tldo/Trp53tm1.1Tldo
Trp53tm1.2Awbr/Trp53tm1.2Awbr
Trp53tm1.2Awbr/Trp53+
Trp53tm1Ldo/Trp53+
Trp53tm1Tyj/Trp53+
Trp53tm3.1Tyj/Trp53+
Tg(Trp53A135V)L3Ber/0
Trp53tm1Brn/Trp53tm1Brn  (conditional)
Trp53tm1Brn/Trp53tm1Brn
Tg(MMTV-cre)105Ayn/0  (conditional)
Trp53tm1Brn/Trp53tm1.1Brn  (conditional)
Trp53tm3Tyj/Trp53+
Tg(Wap-cre)11738Mam/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory